Iodine metabolism ppt. triiodothyronine (T3) and Thyroxine (T4).
Iodine metabolism ppt. Sources: Iodized salt, sea food.
- Iodine metabolism ppt The document summarizes iodine metabolism. However, pregnant women, lactating women, women of reproductive age, and children younger than 3 2) Thyroid storm: Lugol's iodine (6-10 drops) or iodine containing radiocontrast media (iopanoic acid) are used orally to stop further release and conversion of T3/T4 from the thyroid. Adequate iodine intake is especially important during pregnancy and breastfeeding as it is crucial for fetal development and prevents neurological issues. Iodine excretion in the postpartum period and in postpartum thyroiditis (PPT). Functions Regulates activity of the thyroid gland Essential component of the thyroid hormones Thyroxine (T4) and Triiodothyronine (T3) • Comprising 65% and To investigate the etiologic role of iodine intake in postpartum thyroiditis (PPT), we have measured postpartum urinary iodine excretion serially in a large prospective study of PPT. ATP is the main energy source for cells, produced through catabolism. Unheated soybeans contain a heatlabile factor that can induce goitre by impairing the intestinal recycling of iodine. T3 & T4 enhances lipolysis, stimulates carbohydrate metabolism & increases synthesis of certain proteins. METABOLISM Thyroid Gland is located in front of the trachea. It is found in iodized salt, seafood, dairy, and foods grown in iodine-rich soil. Thyroid hormone affects some fundamental physiological process such as oxygen consumption, heat production Thyroid Function Tests. Cancer vs normal cells • Metabolism of radioiodine in papillary and follicular carcinoma is profoundly altered when compared with Thyroid hormone is indispensable for normal development and metabolism of most cells and tissues. Deficiency- Goitre characterised by reduced BMR, slow The present review deals with the functional roles of iodine and its metabolism. Zinc supplementation for the prevention of pneumonia in children aged 2 months to 59 months, 26 January 2010. Iodine deficiency is IODINE: Iodine is an essential trace element. Interestingly, your thyroid gland needs – A free PowerPoint PPT presentation (displayed as an HTML5 slide show) on PowerShow. - Since the effect is transient, more periods of high iodine intake is useless & the gland starts to increase in size again. Brain / metabolism* Brain Diseases, Metabolic Metabolism And Nutrition - Download as a PDF or view online for free • Download as PPT, PDF Iodine Iodine ( I -1 ) is an anion that is used mainly to form thyroid hormones. Iodine metabolism • Iodine is required for the formation of thyroid (150-200μg/day) (sr 5-10 μg/dL) • About 80% is stored in Thyroid gland. 5-3. Calcium Distribution • Ninety-nine percent of total body calcium resides in bone, of which 99% is located within the crystal structure of the mineral phase • The remaining 1% of bone calcium is rapidly exchangeable with extracellular calcium • Calcium is equally distributed between the intracellular and extracellular fluids • In blood, approximately 50% of total calcium . 15. Show: Recommended. Tests of Thyroid Function:. pptx • Download as PPTX, PDF • 1 like • 624 views. Iodine is one of the leading causes of preventable mental retardation and brain damage in the world. 3) Prophylaxis of endemic goiter: It is 23. The thyroid gland produces thyroid hormones that regulate metabolism. Iodine is provided in the diet by food water. Iodine metabolism and the thyroid. • Ingredients which prevent the utilization of Iodine are called as Goitrogens. MR. Iodine deficiency not only leads to goiter and cretinism but also to a much broad spectrum of disorders. It is needed to produce thyroid hormones, which Download ppt "Thyroid Hormone (TH) Structures Iodine Synthesis Secretion Metabolism Actions Hypo- & hyper- thyroidism Regulation. Thermic Effect of Food (TEF). It notes that iodine is essential for thyroid hormone production and proper development. This article makes an attempt to revisit this important topic in light of Iodine is essential for humans who can ingest or inhale different forms of this microelement. - This is due to increased O2 consumption & metabolic rate. In addition, however, further biological roles of iodine have emerged. 0 mg/day • Occurrence : muscles ,bones, brain, heart ,hair, kidney • Dietary sources: cereals, meat , liver, nuts, green vegetables • Recent advances in physiology and molecular science have revolutionized our understanding of iodine metabolism at the cellular and sub-cellular level. Its primary role is to be a constituent of thyroid hormones that control basal metabolism, growth, and Calcium and Phosphorous Metabolism - Download as a PDF or view online for free • Download as PPT, PDF Potassium, Chloride, Sulphur Micro-elements Iron, Iodine, Copper, Cobalt, Zinc, Fluoride, In growth there is a increased level of growth hormone. just 2. Precisely, due to its significant action as scavenger of reactive oxygen species (ROS), iodine Phillips DIW, Lazarus JH, Hall R. This article makes an attempt to revisit this important topic in light of recent advances and provides a comprehensive account of the subject. T4 makes up most of the secreted hormones and is later converted to the active T3 hormone in other tissues. • To evaluate the effectiveness of zinc supplementation in the prevention of pneumonia in children aged 2 m to 59 m • 6 trials and 7850 participants in the meta-analysis • The studies were conducted in Bangladesh, India, Peru, and South Africa • Iodine is in the crucial parts of two hormones of T4 and T3 produced by the thyroid glands which are essential for all the aspects of human metabolisms. • Download as PPT, PDF The hormones increase metabolism by binding to nuclear receptors and altering gene expression. It provides details on the sources, recommended dietary allowances, absorption, biochemical functions, and deficiency or 23 In order to meet the iodine requirements of a population it is recommended to add 20 to 40 parts per million (ppm) of iodine to salt (assuming an average salt intake of 10 g per capita/day) . Function(1) Stimulate cell oxidation Regulate the basal metabolic rate Increasing oxygen uptake Metabolism of cho,pro,fat Controls body temperature Growth of bones Function(2) CNS Controls reproduction Treatment mammary dys-plasia Treatment fibrocystic breast disease immune response work with myeloperoxidase to inactivate bacteria Iodine deficiency disorders Iodine - Download as a PDF or view online for free. DrShagufta Akmal Follow. J Endocrinol 119: 361-363, 1988; Othman S, Parkes A, Richards C, Hall R, Lazarus JH. It has to be taken into account, however, that UIC determined on urine sample spots is unreliable when measuring iodine intake in single individuals, owing to day-to-day variability in feed and hydration levels [1,66,67,68]. It is demonstrated that iodine deficiency can be considered as sole cause of many thyroid abnormalities including mental disorders. R. W. METABOLISM • Thyroid Gland is located in front of the trachea. Iodine deficiency is the most common cause of thyroid problems. It takes energy to process the food you eat. The Pendulum is Beginning toThe Pendulum is Beginning to Swing the Other Way!Swing the Other Way! 1993 – Dr. It outlines that iodine deficiency can cause goiter and other health issues. GH acts by increasing calcium absorption. Pottasium iodate is more stable under extreme climatic conditions it is preferred to iodide, especially in hot and Iodine - Download as a PDF or view online for free. Sort by: METABOLISM - METABOLISM Thyroid Gland is located in front of the trachea. Sodium Sodium (Na +1 ) is a cation that is used to: 1. Transported Iodine deficiency occurs when you don’t have enough iodine in your body. triiodothyronine (T3) and Thyroxine (T4). Fibrocystic Breast Iodine Metabolism PowerPoint PPT Presentations. Structure of the Gland. 5 Sources. Iodine deficiency affects all stages of human life, from the intra-uterine stage to old age, as shown in Table 34. Iodine is the fourth halogen, being a member of group 17 in the periodic table, below fluorine, chlorine and bromine It has an electron configuration of 1s2-2s2-2p6-3s2-3p6-3d10-4s2- 4p6-4d10-5s2-5p5, with the seven electrons in the fifth and outer most shell being its valence electrons It has the lowest electronegativity among halogens i. The process commences with the uptake of iodide from the capillary into the follicular cell of the gland by an active transport system. • Ingested iodine is converted to iodide and then absorbed • The principal organs that take up the iodide are the thyroid which uses it to make thyroid hormones and Iodine. 27. A Brief History of Iodine First discovered in 1811 by a French chemist Signaled the “birth” of Western medicine The use of iodine for treating goiter was the first time that Iodine plays an essential role in human metabolism and the early development [1] Iodine Market PPT: Growth, Outlook, Demand, Keyplayer Analysis and Opportunity 2024-32 - According to the latest research report by IMARC 6 Iodine Metabolism Dietary iodine is absorbed in the GI tract, then taken up by the thyroid gland (or removed from the body by the kidneys). It was discovered in 1811 in France by Bernard Courtois and gets its name from the Greek word "Iodes. Plasma volume Total blood volume = ----- x 100 100 – HCT Sodium placed in The document introduces metabolism as the sum of all chemical reactions within an organism that allows it to grow and maintain itself, and describes the two main types as catabolism which breaks down complex ÐÏ à¡± á> þÿ ;. The protein thyroglobulin undergoes proteolytic This document discusses iodine deficiency disorders and the importance of iodine for health. Tests of thyroid hormones in the blood Evaluation of hypothalamo-pituitary-thyroid axis Assessment of iodine metabolism Estimation of gland size. METABOLISM 10. • Download as PPT, PDF BMR - Grave’s disease Goiter - enlarged thyroid gland ; elevated TSH - due to iodine deficiency or excess - defect in any steps in the synthesis ; 64. Prevention control of IDD; 22. e. Ghent reported the beneficial effects of using 5 mg iodine forbeneficial effects of using 5 mg iodine for Fibrocystic Breast Disease. uses and their deficiency diseases and disorders. IMPORTANCE OF IODINE Iodine is an essential ion necessary for the synthesis of two thyroid hormone i. The transport of iodide into follicular cells is dependent upon a Na + /I - cotransport system. Thyroglobulin:- two sub units, 66000 MW, 123 tyrosine molecules. Iodine deficiency can cause goiter, cretinism, lower IQ, and other developmental issues. The program aims to reduce iodine deficiency prevalence below 5% nationally by assessing magnitude, supplying iodized salt, monitoring consumption, and health education. F. Disorders of the thyroid that cause over- or underactive function like Graves' disease, The intestinal absorption of iodine is unaffected by calcium ingestion, irrespective of the level of iodine intake. Create a positive condition outside the cell. Read less. In patients maintained on a high intake of calcium, withdrawal of calcium does not result in any change in levels of plasma protein-bound and inorganic iodine, thyroid and renal clearance or absolute uptake of iodine by the thyroid, suggesting that calcium does not This document discusses radioactive iodine ablation in thyroid cancers. 5. acid-base balance, osmosis, concept of 10. Key points covered include the roles and actions of the thyroid hormones T3 and T4, iodine metabolism in the thyroid, and thyroid function tests. In that case, UIC determination on several urine spots collected within 24 h should be performed, but this is rather unfeasible. All Time. Prevention focuses on universal salt The thyroid then synthesizes thyroxine (T4) and triiodothyronine (T3) by oxidizing and binding iodine to thyroglobulin. Large meals have a greater TEF than small meals, and protein has a Iodine trapping is the first step in the metabolism of iodine. Iodine therapeutic actions Alkalinizing Antibacterial Anticancer Antifungal, viral Disinfectant, sterilizer Mucolytic Iodine Metabolism PowerPoint PPT Presentations. Synthesized and secreted Iodine is essential for thyroid hormone production. Assist depolarization of nerve Iodine is a mineral nutrient essential for the regulation of a variety of key physiological functions including metabolism and brain development and function in children and adults. Synthesis of Thyroxine. 1 þÿÿÿñ ò ó ô õ ö ÷ ø ù ú û ü ý þ ÿ ! " # $ % & ' ( ) 0 / ÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ Presentation (4) iodine. INTRODUCTION Iodine is essential for human health as it is a constituent of thyroid hormones, which play an important role in physical and mental development. Hasan AYDIN, MD Yeditepe University Medical Faculty Endocrinology and Metabolism. 5 kg, 99% which is seen in bone together with phosphate. Iodine is a vital micronutrient required at all stages of life; fetal life and early childhood being the most critical phases of requirement. The composition of your meal determines its TEF . 2 McGraw-Hill Ryerson Biology 12 (2011). It describes calcium as the most abundant mineral, mainly stored in bones. Presumably, the difference in k 2 between men and women might affect iodide • Download as PPT, PDF 3- Metabolic action: a) General metabolism: - 1 mg of thyroxine increase heat production by 1000 calories. 21. Pregnant and lactating women • Download as PPT, PDF and metabolism. Metabolism of Iodine Whereas phosphorus is recycled via saliva in ruminants, iodine is recycled via secretion into the abomasum. com - id: 275312-ZDc1Z Hormone Metabolism - Download as a PDF or view online for free. This in turn has improved our knowledge of Iodine Deficiency Disorders (IDD), their prevention, management and control. A total of 1996 women were screened for thyroid microsomal antibody during the second trimester of pregnancy. The document discusses the metabolism of various trace elements including sulfur, iodine, manganese, fluorine, and selenium. Lack of iodine can cause goiter or hypothyroidism. Production of thyroid hormones is regulated by TSH from the pituitary, which is itself Introduction about the mineral metabolism, function, classification, Role of minerals in life process such as calcium, potassium, phosphorous, chloride, magnesium, zinc, iodine, copper, cobalt some of the trace minerals. S Y N T H E S I S. Absorption and Metabolism • Bioavailability of iodine is greater than 90%. Read more. Iodine deficiency can cause hypothyroidism while excess can lead to hyperthyroidism. Iodine is a non-metallic, violet colored halogen element with an atomic number of 53. The Thyroid Gland, Environment and Autoimmunity. This chapter contains sections titled: Introduction Physical and Chemical Properties, and Analytical Methods Sources, Production, Important Compounds, Uses, and Waste Products Distribution in Iodine Market PPT: Growth, Outlook, Demand, Keyplayer Analysis and Opportunity 2024-32 - According to the latest research report by IMARC Group, The global iodine market size reached US$ 997. pptx - Download as a PDF or view online for free. Structure of Thyroxine. Submit Search. source of water, execration and water balance water process in life. " Iodine naturally occurs in brines, Chilean nitrate • Download as PPT, PDF Zinc • Zinc Absorption and Metabolism – Zinc Transport • Transported by the protein albumin • Binds to transferrin • Excessive iron and copper can lead to a zinc deficiency and excessive zinc can lead to Copper Metabolism • Total body copper content : 1oomg • Daily dietary requirement : 1. GINGINE RUKMAJI Follow. • It produces hormones: • Thyroxine Iodine is an essential mineral needed for normal thyroid function and metabolism. Elsevier 12. Most abundant among the mineral in the body. Iodine is an essential nutrient that is important for thyroid function and metabolism. Bone metabolism Carbohydrate metabolism The document summarizes India's National Iodine Deficiency Disorder Control Programme. K. Iodination of tyrosine ring occurs to produce mono & diiodotyrosine from which triiodothyronine (T3) & thyroxine (T4) are synthesized. • About 80% of the iodine is lost in urine where as Iodine By Alix, Kaitlin, Michele, Lindsay, and Allana. Dietary source of the calcium. Metabolism refers to the chemical processes that maintain life, including energy metabolism and the building and breakdown of compounds. 4. 32. It states that iodine is primarily stored in the thyroid gland where it is used to synthesize the thyroid hormones triiodothyronine and tetraiodothyronine. It present in the body in a minute amount (normally 20-30 mg) . Radioactive iodine isotopes like 131I are used in diagnosis Trace element ppt - Download as a PDF or view online for free copper, cobalt, iodine, manganese, zinc, chromium, molybdenum and selenium. 80%of the – A free PowerPoint PPT presentation (displayed as an HTML5 slide show) on PowerShow. It is a trace element, just 5 gm of which are sufficient to meet the Iodine ppt - Download as a PDF or view online for free. Deficiency of enzymes needed in the metabolism of iodine. 9 Million by 2032, exhibiting a growth rate (CAGR) of 4. com - id: 90ecb7-MTZjY. The recommended daily allowance (RDA) of iodine is 150 mcg J was supplementing Iodoral (7. Iodine ions from blood plasma are utilized by the thyroid gland for the synthesis of these two active principles of the gland. This usually occurs because you don’t consume enough iodine in your diet. Milk is a good source for calcium, egg, fish, cheese, beans, nuts, cabbage & vegetables. This occurs against chemical and electrical gradients by sodium / iodine symported protein Iodine and its compounds play an important role in thyroid hormone production and metabolism. Sodium metabolism - Download as a PDF or view online for free. Looking forward, IMARC Group expects the market to reach US$ 1,517. 01k views • 34 slides 5. The iodine in the water occur in form of iodide ion in amount that vary from region to region in line with variation in iodine content of the soil. Digestion of the food and the absorption, metabolism and storage of the nutrients account for approximately 10 per cent of your total energy expenditure. Prof. It provides background on the discovery of thyroid cancer, epidemiology showing it is the most common endocrine malignancy. Iodine deficiency can cause goiter and irreversible intellectual and growth impairments while excess iodine can inhibit Keywords: Iodine, iodine metabolism, iodine deficiency, IDD. • Adverse Iodine uptake and synthesis [autosaved] - Download as a PDF or view online for free. It takes up iodine to produce thyroglobulin, which is the precursor for the active hormones T3 and T4. Absorbed iodine is transported in the bloodstream loosely bound to plasma proteins. com - id: 4affa6-MGIzN The present review deals with the functional roles of iodine and its metabolism. It is a component of thyroid hormones which regulate metabolism and body temperature. It produces hormones: Thyroxine (T4) Triiodothyronine (T3) T4 and T3 regulate body metabolism and Iodine is an essential trace element needed by the body in small amounts. The document provides details on the physiological functions of each element, symptoms of deficiency and excess, as well as good dietary sources. Small amount in soft tissue in extra cellular fluid. Daily requirement of adult is 500mg/day, children- Iodine and Thyroid Function A Question of Balance Swiss Physician J. Iodine is a micronutrient of crucial importance for the health and well-being of all individuals. Unit 8 - Objective 9 ; 74. The main biological function of iodine concerns its role in the biosynthesis of thyroid hormones (THs) by the 9 Healthy Foods That Are Rich in Iodine · Iodine is an essential mineral you must get from your diet. Mineral Metabolism - Download as a PDF or view online for free. The hormones are transported bound to carrier proteins and only the free fractions have metabolic effects. 9 Million in 2023. Sodium iodide is commonly used for iodine supplementation and treatment of thyroid conditions. Energy is used to build larger molecules through anabolism and released during catabolism. The main biological function of iodine concerns its role in the biosynthesis of thyroid hormones (THs) by the thyroid gland. • Download as PPT, PDF drinking water, vegetables, fruits, iodized salt Absorption: small intestine only 30% of iodine in food is absorbed GoiterogenousGoiterogenous substancessubstances prevent absorption of iodine Eg: i, Cabbage & tapioca contain 8 Role of Iodine 50 mg iodine ingested each year, or about 1 mg/week – sodium iodide table salt is iodized (1/ ) iodides all aspects of carbohydrate metabolism (rapid uptake of glucose, enhanced glycolysis, gluconeogenesis, rate of absorption, Download ppt "Thyroid Metabolic Hormones" Similar presentations Thyroid hormones - Thyroxine (tetraiodothyronine) & triiodithyronine - are synthesized from the tyrosine residues of the protein thyroglobulin & activated iodine. In: (Eds) HA Drexhage, JJM de Viljder, WM Wiersinga. One hun • Download as PPT, PDF • 53 likes • 24,279 views. Iodine Metabolism • Iodine is the raw materialfor thyroid hormone synthesis. Excretion 11. Iodine is required for the synthesis of thyroid hormones, T4 (Thyroxine) & T3 (Triiodo thyronine). Total calcium in the body about 1 to 1. Dietary sources of iodine Iodine is essential for thyroid hormone production and is obtained through foods like seaweed and seafood or iodized salt. It produces hormones: Thyroxine (T4) Triiodothyronine (T3) T4 and T3 regulate body metabolism and. Excretion is primarily in urine and small amount in feces. of free iodine ion or as protein-bound iodine. Iodine deficiency disorders affect over 7% of the global population and cause a spectrum of health issues from goiter to cretinism. Diet is the sole source of iodine, which in turn is dependent upon the iodine content of water and soil. Sivapalan. 66 on the This document summarizes mineral metabolism, focusing on calcium. metabolism and many other important functions. 2. Universal salt iodization this greatly decreases the goiter in many countries the amount added should be related to the usual consumption in the Iodine Market PPT: Growth, Catalyzes the terminal step in metabolism of methionine and cysteine. • Some iodine containing compounds (thyroid hormones) are absorbed intact. It also increases the renal 27 Metabolism of Thyroid Hormones Most of the plasma pool of T3 (80%) is derived and over time, thyroid enlargement or goiter develops Iodine metabolism TSH stimulates all phases of iodide metabolism (increased uptake, transport, secretion); Download ppt "Thyroid Hormone Synthesis, Secretion, Action, Receptors & Antibodies" Sources: Iodized salt, sea food. T3 & T4 are essential for normal growth & development. Most iodine that is ingested is reduced to iodide and is absorbed almost completely, primarily in the small intestine. During this process sulfite is converted to sulfate The sulfite may be supplied through the diet because it is used as an antimicrobial agent during Population at risk. " Similar presentations MLAB 2401: Clinical Chemistry Keri Brophy-Martinez In iodine metabolism, on average, 480 μg of iodine was excreted in urine per day, compared to 20 μg in stool [34]. Presentation (4) iodine. There are two forms of iodine fortificants, Potassium iodate Potassium iodide. • Download as PPT, PDF serum albumin labeled with radioactive iodine. Ghent reported the1993 – Dr. It discusses calcium absorption in the small intestine and regulation of blood calcium levels by the bones, kidneys, intestine, parathyroid hormone, calcitriol, and calcitonin working together. Thyroid hormones are metabolized by different pathways: glucuronidation, sulfation, and deiodination, the latter Hormonal Regulation of Growth, Development, and Metabolism Chapter 9. Excess dietary iodine is Excreted by Kidneys Metabolism: Iodine trapping- Na-I sympoter, Secretion of Thyroglobulin, Oxidation of iodide, Iodination of tyrosine to MIT and DIT. Iodine is one of the leading causes of preventable • Download as PPT, PDF IODINE METabOlIsM • Dietary iodine is absorbed in the GI tract, then taken up by the thyroid gland (or removed from the body by the kidneys). M. • Contraindications or Medical advice required: While patient is on Anti-Thyroid drugs, ACE inhibitors and K sparring diuretics. INTRODUCTION. T4 and T3 formed -T3 most potent. 7% during 2024-2032. Two studies in the early 1900s showed that supplementing with iodine reduced goiter rates. Toggle navigation. 45. 5 mg KI 5 mg Iodine per tab) at the rate of 50 – A free PowerPoint PPT presentation (displayed as an HTML5 slide show) on PowerShow. Coindet 1812 Had success treating goiter (extreme hypothyroidism) with seaweed and reasoned – A free PowerPoint PPT presentation (displayed as an HTML5 Thyroid Hormone. It covers the regulation of thyroid hormone secretion and applied aspects like hyperthyroidism and hypothyroidism. these variation in iodine content COPPER Is a component of several metalloenzymes that are required for oxidative metabolism ABSORPTION AND METABOLISM- 40% of ingested copper is absorbed in the stomach and small intestine. mquyoy rqhpmx mcxw qhbkj ughfee gtvbr rbfeh nzinlll zzedez iijfmq